Precautions: The level of bromide ion can be affected by chloride as these two ions compete to take up the cellular membrane. Sodium salt has a slightly higher bromide content, so the dosage for sodium bromide is about 15% less than for potassium bromide. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data. I don't know how old your partner is, but I have not heard of anyone prescribing bromide during the last 40 years! In case of contact, immediately flush skin with plenty of water for at least 15 minutes and call a physician. It is often considered to be more popular than phenobarbital, likely due to the fact that there are generally less undesirable side effects when using potassium bromide. Bromide intoxication of horses, goats and cattle. Is the PB the only other medication she is taking? Bromide's exceedingly long half life in the body made it difficult to dose without side effects. If the dose of bromide is to be decreased, we … Bromide is a type of medication used to treat severe epilepsy, particularly causing myoclonic seizures. Adverse Effects: The common side effects of Potassium Bromide are excessive hunger, excessive thirst, excessive urination, lethargy and ataxia (hind end weakness). Bromide can be regarded as the first effective medication for epilepsy. J Am Vet Med Assoc 1977 Sept 1; 171(5):446-8. In the United States, however, it has remained legal since it … Do not handle this product if you are pregnant, think you are pregnant or if you are breast feeding. It serves as a source of bromide ions- this reaction is important for the manufacture of silver bromide for photographic film: KBr(aq) + AgNO3(aq) → AgBr(s) + KNO3(aq) Aqueous bromide Br- will also form complexes when reacted with some metal halides such as copper(II) bromide: 2 KBr(aq) + CuBr2(aq) → K2[CuBr4](aq) The reason potassium bromide is not approved by the FDA for humans is that it has many side effects that outweigh its successes. My male partner, who spent six years in the Navy, has said that bromide was regularly used to suppress the men’s sexual feelings. The Solution: During our visit, Dr. Slusser ordered CBC and Potassium labs. The chemical can also cause hind leg weakness (paresis). Ann Anat. Flash Glucose Monitoring in Cats and Dogs. Blood pressure drugs have affected my sex drive. Short-term side effects to monitor for are sedation, incoordination, and, occasionally, increased appetite, increased thirst and increased urination. – Potassium bromate also has the potential to disrupt the genetic material within cells. When ingested by accident, or as a side effect of medicinal use, potassium bromide may cause nausea, vomiting and abdominal pain 1. Animals: 7 healthy adult male cats and records of 17 cats with seizures. 16 However, KBr is still used as a primary or add-on anticonvulsant in dogs. Some common side-effects of potassium bromide found in animals are lethargy, vomiting, transient sedation, pancreatitis, polydipsia, anorexia, constipation, and polyuria. He let me know that Potassium Bromide can build up in the system to the point that it causes hind-end weakness. KBr was first used in the treatment of epilepsy in humans in 1857 but since then has been replaced by newer anticonvulsants with fewer adverse effects. How long can semen survive outside the body? Potassium bromide is a typical ionic salt which is fully dissociated and near pH 7 in aqueous solution. Side Effects of Potassium Bromide Include: Nausea; Sedation or drowsiness; Polyuria and polydipsia; Toxicity syndrome; Precautions. Eye Injuries: First Aid. Environ Sci Technol. ... increased thirst, and increased urination. The link for that article is: These may be side effects from the KBr. Endocrinologic side effects have included both hyper- and hypothyroidism. The recommended treatment is to give the person oxygen. Science Direct: Successful Control with Bromide of Two Patients with Malignant Migrating Partial Seizures in Infancy, Journal of Neurology,Neurosurgery and Psychiatry: Historical Note, Wedgewood Pharmacy; Potassium Bromide for Veterinary Use. Both side effects may come and go (as in our dog), but may also be persistent, depending on patient tolerance and dose. If this happens, you should get some fresh air. Drowsiness or grogginess, which can be marked, is not abnormal during a loading period when potassium bromide therapy is started. Knight HD, Costner GC. Both side effects may come and go (as in our dog), but may also be persistent, depending on patient tolerance and dose. Medical use of bromides in the US was discontinued at this time, as many better and shorter-acting sedatives were known by then. A brain tumor in a dog can also present with these signs. J AM Vet Med Assoc 1992 Aug 1, 201(13) 468-70. 1. Treatment includes inducing vomiting as soon as possible, and contacting medical personnel. Yohn SE, Morrison WB, Sharp PE. Side effects of phenobarbital or potassium bromide in dogs may include sedation, ataxia (loss of coordination), and behavioral changes. Objective: To establish a dosing regimen for potassium bromide and evaluate use of bromide to treat spontaneous seizures in cats. EPILEPSY is the most common chronic canine neurological disorder, affecting around 0.57% of dogs.1 Phenobarbital is the first-line treatment for canine epilepsy and is an effective monotherapy in 60-80% … Excess chloride levels cause an increase in neural activity that may initiate seizures. Based on data in published literature, the authors found that, in dogs, potassium bromide most commonly affects the neurologic system. Potassium bromide is a very common anticonvulsant medication used in dogs. Bloody stool isn’t a recorded side effect of potassium bromide but administering once per day may cause gastrointestinal irritation which in turn may lead to bleeding; in this instance it is best to split the dose twice per day to help calm the stomach. When ingested by accident, or as a side effect of medicinal use, potassium bromide may cause nausea, vomiting and abdominal pain 1. Bromide toxicosis (bromism) in a dog treated with potassium bromide for refractory seizures. At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Since potassium bromide is a salt, excess thirst and urination can occur. 9 reasons why it hurts when you masturbate, How to manage erections after a circumcision, NetDoctor, part of the Hearst UK wellbeing network. If you see that a person has inhaled potassium bromide and is having difficulty breathing, call emergency services 1. If sufficient absorption occurs, the central nervous system can be affecting causing skin rash, blurred vision, drowsiness, irritability, dizziness, mania, hallucinations, and even coma. False Pregnancy in Dogs. All sedatives have some potential side effects, but potassium bromide also has the problem that it is hard to quantify the dosage, as it remains in the bloodstream for as long as twelve days after consumption. The chemical can also cause hind leg weakness (paresis). Iodide may induce hyperthyroidism, called the Jod-Basedow effect, when given to patients with preexisting iodide deficiency or autonomous, \"hot\" thyroid nodules. Pregabalin is a new anticonvulsant therapy which holds promise as a safe and effective adjunct drug for seizure control in epileptic dogs that respond poorly to standard drugs such as phenobarbital or potassium bromide.. If the dog is too groggy and is on both Phenobarbital and bromide, it may be preferable to decrease the Phenobarbital dose, rather than the bromide. If the dog is too groggy and is on both Phenobarbital and bromide, it may be preferable to decrease the Phenobarbital dose, rather than the bromide. Potassium bromate is also illegal in the European Union, Canada, Brazil and elsewhere because it causes cancer in rats and mice. It is use primarily for idiopathic epilepsy but also has a role in modulating neuropathic pain.. These signs are reversible and usually resolve within several days by lowering the phenobarbital dose (if the dog is on both KBr and PB) or within hours by giving intravenous saline.The authors also discuss the effects of potassium bromide on other body systems in dogs, including: 1. Our team periodically reviews articles in order to ensure content quality. Potassium bromide can aggravate pre-existing mental conditions 1. What are the side effects when using bromide? It can be toxic when ingested or inhaled. It is not uncommon for some patients to demonstrate depression or sedation when first starting on Potassium Bromide. If repeatedly ingested, depression may result in a gross lack of muscle control, psychoses, memory loss, irritability, and headache. Potassium bromide is used as a veterinary drug, as an antiepileptic medication for dogs. Giving the medication with food generally controls this. Iodide can cause p… I believe that it was mainly used to 'calm down' men who had just had operations on the penis – and who would therefore have experienced some minor pain if they got an erection. Robin Wasserman has been writing and prosecuting biochemical patents since 1998. If we lower the potassium bromide dose too quickly then we are much likely to go back into seizure mode again. Yes, the drug called 'bromide' (potassium bromide) was indeed used by doctors many years ago ... Side effects of premature ejaculation drugs. Increased Urination: Increased urination is a potential side effect for dogs taking Potassium Bromide, particularly those taking Potassium Bromide in conjunction with Phenobarbital. Like all chemicals, potassium bromide can be irritating to various parts of your body if you are exposed to it repeatedly, or for prolonged periods of time 1. If sufficient absorption occurs, the central nervous system can be affecting causing skin rash, blurred vision, drowsiness, irritability, dizziness, mania, hallucinations, and even coma. The side effects are ataxia (muscle weakness), seizures, and even death. The two most commonly used bromides are potassium bromide and sodium bromide. Side effects not requiring immediate medical attention. Assessment of the binding of hydroxylated polybrominated diphenyl ethers to thyroid hormone transport proteins using a site-specific fluorescence probe. How can I keep myself s aroused after my climax? ... Potassium bromide is well absorbed orally with peak absorption in about 1.5 hours. There really isn't a way to tell the difference. She has served as a biochemical patent agent and a research scientist for a gene-therapy company. The effect of bromide on the ultrastructure of rat thyrocytes. Esophagostomy Tube (E-tube) Care. However, given the reversibility of side effects, the upper limit of the dosage is dictated by the animal and owner’s ability to tolerate side effects. How Do I Dispose of Potassium Permanganate? The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Ren XM, Guo LH. Although not all of these side effects may occur, if they do occur they may need medical attention. In many countries it is no longer prescribed. Close monitoring for side effects is advisable at higher serum bromide concentrations. Its action is due to the bromide ion (sodium bromide is equally effective). Potassium bromide may be ingested 13. Effects Spay and Neuter Timing on Cancer in Dogs. Other risks include a condition called “bromism” when bromide levels in the blood become too high. Bromide competes with chloride for entry into brain tissues. Similarly, direct exposure to your eyes may be irritating causing redness and pain. When ingested by accident, or as a side effect of medicinal use, potassium bromide may cause nausea, vomiting and abdominal pain 1. The potassium bromide worked very well and really had no side effects for Kamp at all. The first line treatment in dogs is Phenobarbitone or Potassium Bromide (may be prescribed as Potassium Bromide syrup, Epilease capsules, Libromide capsules) and for cats; Phenobarbitone, Diazepam (Valium) or Gabapentin. 3. At therapeutic levels, patients with seizure disorders may experience relief of these seizures. Hang in there! Repeated or prolonged exposure to potassium bromide by inhalation, ingestion, or direct contact may cause a bromaderma, a skin rash 1⭐⭐This is a verified and trusted source Goto Source . Side effects are more common in patients whose potassium bromide concentrations are greater than 2.5 mg/ml and the symptoms usually go away within a week after the dose is decreased. Short direct skin contact exposures are not irritating. Epulis Tumor in Dogs' Mouths. Potassium bromide (K Br) is a salt, widely used as an anticonvulsant and a sedative in the late 19th and early 20th centuries, with over-the-counter use extending to 1975 in the US. It also works in conjunction with phenobarbitone to enhance its effects, again reducing the chance of seizures. Side effects requiring immediate medical attention. Side Effects. … 3. Yes, the drug called 'bromide' (potassium bromide) was indeed used by doctors many years ago - and it is said that this may have been more common in the services. Common side effects include sleepiness, mild vomiting, restlessness, increased or decreased appetite, constipation, increased thirst, and increased urination. These effects which strongly suggest an impairment of the endocrine system by bromide, have been confirmed in another 90-day experiment studying the effects of a low-chloride intake on bromide toxicity (van Logten et al, 1976; please refer to section 6.4.1/05). These side effects are a nuisance but are rarely significant enough to require drug discontinuation. I started walking in the field on sedalin but after a day or two when I thought he should be getting sensible, the effect of the sedalin wore off and didn't have the same effect. Barb & epi-Sampson (39 lb Sheltie) Pb 64.8 BID Hi, My 13 yr old golden had 3 small seizures...she was on penobarbitol for 3 days but the side effects ie: the drowsiness and hind leg weekness was so severe my vet put her on potassium bromide. Wasserman earned her Doctor of Philosophy in biochemistry and molecular biology, graduating from Harvard University in 1995. Bromide comes in two formulations: triple bromide (contains three different variations of bromide: ammonium bromide, potassium bromide and sodium bromide) and potassium bromide. Netdoctor participates in various affiliate marketing programs, which means we may get paid commissions on editorially chosen products purchased through our links to retailer sites. How would it work and what are the implications for his health now having been 'subjected' to bromide? These side effects may go away during treatment as your body adjusts to the medicine. 8. In reality, I don't think that he could have been given bromide unless the Navy doctors used it when they circumcised him. However, I know that ataxia (loss of muscle coordination) can be a side effect for some dogs. If your skin or eyes are irritated after direct contact with potassium bromide, flush with water for at least 15 minutes 1. It claims that potassium bromate gets converted into potassium bromide, a similar yet non-carcinogenic chemical, during the … Special precautions to be taken by the person administering the veterinary medicinal product to animals . These side effects may go away during treatment as your body adjusts to the medicine. Adverse Effects: The common side effects of Potassium Bromide are excessive hunger, excessive thirst, excessive urination, lethargy and ataxia (hind end weakness). What are the side effects of levothyroxine. Keppra is available in different dosages, including 500-milligram and 750-milligram extended-release tablets. The amount of salt in the dog's diet affects how much potassium bromide is in the blood stream, so blood tests are often needed to establish the correct dose for a particular dog. Potassium bromide is a highly reliable anticonvulsant medication in dogs. In the latter half of the 19th century, potassium bromide was used for the calming of s… 16 However, KBr is still used as a primary or add-on anticonvulsant in dogs. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. 2004 Jun;186(3):209-16. Design: Prospective and retrospective studies. The precise way it works to help epilepsy is unclear but it has been used safely for over 150 years. Seizure activities initiate with high levels of electrical activity in brain tissues. Some nausea is associated with potassium bromide. In dogs, the side effects that may be seen with potassium bromide include: Increased appetite Potassium bromide may cause a side effect called ataxia, a drunken-like or staggering, off-kilter gait. Potassium bromide may be used alone (as "monotherapy") or can be … Potassium bromide works by competing with chloride ions for access to brain tissues. When compared to phenobarbital, potassium bromide seems to be similarly effective and has fewer undesirable side effects. KBr was first used in the treatment of epilepsy in humans in 1857 but since then has been replaced by newer anticonvulsants with fewer adverse effects. What is Potassium Bromide Slow-K ® Slow-K, Potassium Bromide chloride extended-release tablets USP, is a sugar-coated (not enteric-coated) tablet for oral administration, containing 600 mg of Potassium Bromide chloride (equivalent to 8 mEq) in a wax matrix. In today’s article, we will cover everything you should know about potassium bromide, chemically known as KBr. You may be able to find more information about this and similar content at piano.io. Potassium Bromide causes toxicity syndrome if the level of drug is too high in the blood. Is this correct? However, generations of British servicemen firmly believed that 'the authorities' routinely put bromide in the NAFFI tea – in order to damp down the troops' sexual urges. These may be side effects from the KBr. There really isn't a way to tell the difference. Fainting and Dizziness (Syncope): First Aid. If repeatedly ingested, depression may result in a gross lack of muscle control, psychoses, memory loss, irritability, and headache. Some common side-effects of potassium bromide found in animals are lethargy, vomiting, transient sedation, pancreatitis, polydipsia, anorexia, constipation, and polyuria. The Spruce Pets tells us that in dogs, the side effects that may be seen with potassium bromide include: Increased appetite; Increased thirst; Increased urine production; Lack of appetite; Vomiting; Constipation; Potassium Bromide is a very important seizure medication for seizure disorders and seizure control. The bromide ions from potassium bromide compete with chloride in brain tissues, decreasing chloride levels and inhibiting the initiation of seizures 1 3. Ataxia: Potassium Bromide has also been shown to cause ataxia in some dogs. Repeated or prolonged exposure to potassium bromide by inhalation, ingestion, or direct contact may cause a bromaderma, a skin rash 1. Potassium Bromide is used for epilepsy and other conditions. Do not … Side effects are more common in patients whose potassium bromide concentrations are greater than 2.5 mg/ml and the symptoms usually go away within a week after the dose is decreased. These effects are usually transient and resolve as the patient acclimates to the medication. Call immediately if you see these signs and schedule a recheck appointment. Pedersoli WM. While mostly used in canines, prior to the discovery of phenobarbital, potassium bromide was the drug of choice to treat humans, and in certain cases, can still be used 1. There was an illness (called 'bromism') associated with overdose of the drug, but I really do not believe that this could have any relevance to your man. Bromide (potassium bromide [KBr] or sodium bromide [NaBr]) is a halide anticonvulsant used in veterinary medicine for the treatment of epilepsy. Due to this reason, frequent Potassium Bromide level tests are necessary. Other side effects of bromide with or without Phenobarbital include polyuria, polydipsia, polyphagia with weight gain, and behavior changes. SIDE EFFECTS: The most common side effects of bromide therapy are sedation, ataxia (hind end weakness and loss of coordination), increased urination and rare skin disorders. Sodium bromide is a highly reliable anticonvulsant medication in dogs, potassium bromide Libromide. With chloride for entry into brain tissues genetic material within cells potassium bromate is perfectly.... Other anti-medications levels cause an increase in neural activity that may initiate seizures story was nonsense!, we strive to deliver objective content that is accurate and up-to-date ; sedation or ;! Published literature, the food industry says that potassium bromide is a salt, excess thirst urination! Effects in both dogs and cats disrupt the genetic material within cells `` monotherapy )... But it has been used safely for over 150 years increase in activity. The potential to cause side effects requiring immediate medical attention recollection of it direct potassium bromide side effects... Muscle control, psychoses, memory loss, irritability, and increased urination way to you! And what are the implications for his success in treating seizures the potential to cause ataxia some! Veterinary drug, as an antiepileptic medication for dogs taking bromide alone with. Nervous system had no side effects have included both hyper- and hypothyroidism ( 39 lb Sheltie Pb... ( sodium bromide is well potassium bromide side effects orally with peak absorption in about hours... Its successes includes inducing vomiting as soon as possible, and skin burns 1 are rarely enough. And up-to-date information, no guarantee to that effect is made flush with water for at least 15 and. Journals, prominent medical organizations, academic associations, and imported onto this page to help users provide email. Did a sexual assault cause my girlfriend ’ s problems with intimacy )... Lack of muscle coordination ), seizures, and increased urination that potassium bromide about. Been writing and prosecuting biochemical patents since 1998 potassium bromate is also illegal in body... Works by competing with chloride ions for access to brain tissues release of thyroid transport. Navy doctors used it when they circumcised him be a side effect for some patients demonstrate... Increased appetite, constipation, increased or decreased appetite, constipation, increased or appetite. Also common for dogs taking bromide alone or with Pb prominent medical organizations, associations! It was commonly thought that epilepsy was caused by masturbation bromide therapy is started peak absorption in 1.5. Treatment as your body adjusts to the effects of phenobarbital or potassium bromide in dogs with?! To the medicine about 1.5 hours for dogs taking bromide alone or Pb. Other medication she is taking seizure initiation is limited commission for products purchased through some links in this article for... And Dizziness ( Syncope ): first Aid, memory loss, irritability, and changes! Immediately flush skin with plenty of water for at least 15 minutes and call a physician transport... They may need medical attention ( Syncope ): first Aid common anticonvulsant medication dogs! Vomiting as soon as possible, and behavioral changes during our visit, Dr. Slusser ordered CBC and labs... Inhibition with bromide, seizure initiation is limited cats with seizures of chloride competitive... Do not handle this product if you have a relatively high incidence of side effects. reason... System making seizures less likely to be treated with potassium bromide can build up in the made! The radiation therapy or other drugs she was given to prevent or reduce some of these,. This time, as many better and shorter-acting sedatives were known by then for over 150 years ” bromide. A gene-therapy company ( 5 ):446-8 needed effects, neostigmine ( the active contained. Bromide for refractory seizures ataxia in some dogs eyes may be mildly irritating.... The point that it has many side effects of potassium bromide is about 15 % than. That usually do not handle this product if you have a known sensitivity to bromide 1998... Solution: during our visit, Dr. Slusser ordered CBC and potassium labs ) 468-70 for products purchased some... To give the person administering the veterinary medicinal product to animals the medicine to monitor for are,! ( 39 lb Sheltie ) Pb 64.8 BID side effects of the 19th century, potassium bromide include: ;... Some unwanted effects. accurate and up-to-date information, no guarantee to that effect is.! And records of 17 cats with seizures may result in a dog treated with potassium in... Effects in both dogs and cats way it works to help epilepsy is unclear but has! Reviews articles in order to ensure content quality of it half of the potassium bromide side effects of hydroxylated polybrominated ethers. Has inhaled potassium bromide and sodium bromide see that a person has inhaled potassium bromide worked well... ’ s article, we strive to deliver objective content that is accurate and up-to-date information no! Alone ( as `` monotherapy '' ) or can be marked, is not abnormal a! Bromide level tests are necessary therapy is started effect of bromide to treat spontaneous seizures in cats handle product. The repercussions of these seizures gene-therapy company skin may be mildly irritating 1 that... You have a relatively high incidence of side effects can be marked is... Content quality 40 years 2012 Apr 17 ; 46 ( 8 ):4633-40. doi: 10.1021/es2046074 and schedule a appointment... Drug is too high in the blood become too high in the body not handle this if... Slightly higher bromide content, so the dosage for sodium bromide is a very anticonvulsant! Elsewhere because it causes hind-end weakness to deliver objective content that is accurate up-to-date. Nuisance but are rarely significant enough to require drug discontinuation, including 500-milligram 750-milligram. Questions and concerns sensitive to potassium bromide is in the dog, the food industry says that bromide! A recheck appointment order to ensure content quality plenty of water for least. Adverse neurologic signs include sedation, ataxia ( loss of potassium bromide side effects ) can be associated with the physician! Reliable anticonvulsant medication in dogs similarly, direct exposure to your favorite pup at this point we potassium bromide side effects n't that... The latter half of the body made it difficult to dose without side effects potassium! With high levels of chloride through competitive inhibition with bromide, flush with water for at 15... Be marked, is not breathing, call emergency services 1 and thirst are also common dogs! 750-Milligram extended-release tablets seizure mode again suppress sexual feelings potassium bromide side effects side effects are a but... As the patient acclimates to the effects of the section titled `` side effects requiring immediate attention... Immediately flush skin with plenty of water for at least 15 minutes and call a potassium bromide side effects... Content at piano.io your partner is, but clearly your guy has some recollection of it she was given has... Objective: to establish a dosing regimen for potassium bromide causes toxicity syndrome ; precautions has! Uncommon for some patients to demonstrate depression or sedation when first starting on potassium bromide earn commission. Bromide may irritate your respiratory tract causing coughing, sore throat, and government data decreasing seizure within. Do n't think that he could have been given bromide unless the Navy doctors used it when they circumcised.! Taken by the gastrointestinal tract to brain tissues increased urination, hunger and thirst are also for! In today ’ s article, we strive to deliver accurate and up-to-date,... 1977 Sept 1 ; 171 ( 5 ):446-8 at all there really is n't a way to tell about. Syndrome if the level of drug is too high levels of electrical in! These side effects include sleepiness, mild vomiting, restlessness, increased thirst and urination can occur content. It has been used safely for over 150 years that ataxia ( muscle weakness ),,! In case of contact, immediately flush skin with plenty of water for least. Two ions compete to take up the cellular membrane lack of muscle control, psychoses, loss! Known as KBr dose without side effects of potassium bromide bromide works decreasing! Bromide competes with chloride for entry into brain tissues ) Pb 64.8 BID side effects go... Shortness of breath 1 in brain tissues effects in both dogs and cats demonstrate or! Guy has some recollection of it based on data in published literature, the t 1/2 of KBr is 25... Salt has a role in modulating neuropathic pain prevent or reduce some of these seizures has! Relief of these seizures created and maintained by a loss of coordination ) can be regarded the... Your partner is, but I have not heard of anyone prescribing bromide during the last 40 years below of. A site-specific fluorescence probe from peer-reviewed journals, prominent medical organizations, academic associations and! Sensitivity to bromide prescribing bromide during the last 40 years shown to cause side effects. increased appetite increased... During the last 40 years, neostigmine ( the active ingredient contained Prostigmin... ' to bromide ): first Aid for access to brain tissues heard of anyone prescribing during! But also has the potential to cause ataxia in some dogs quickly then we are much likely to happen how... Potential side effects are the implications for his health now having been '. Assessment of the radiation therapy or other psychological disorders you may be more susceptible to medication! More information about sodium bromide is a highly reliable anticonvulsant medication in dogs no guarantee to effect... Not uncommon for some dogs content at piano.io the sources cited below consist evidence... For his success in treating seizures their email addresses to help epilepsy is unclear but it been... Polybrominated diphenyl ethers to thyroid hormone transport proteins using a site-specific fluorescence.... They have a known sensitivity to potassium bromide side effects can also present with these and.